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DESCRIPTION
TREXJOY contains methotrexate which belongs to the class of medications called antimetabolites. It is used to treat a severe form of psoriasis when other treatments are not effective. Psoriasis is an autoimmune disorder that causes your skin cells to grow and multiply much quickly than normal cells. The rate of production of epithelial cells in the skin is highly increased over normal skin. This abnormal cell multiplication causes patches of your skin to become thick and scaly. Methotrexate is active against rapidly multiplying cells, because of its cytotoxic effects that occur primarily during S phase of cell division. It kills the rapidly multiplying cells in the skin.